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HIV Infections. --- Reproduction. --- Human Reproductive Index --- Human Reproductive Indexes --- Reproductive Period --- Human Reproductive Indices --- Index, Human Reproductive --- Indexes, Human Reproductive --- Indices, Human Reproductive --- Period, Reproductive --- Periods, Reproductive --- Reproductive Index, Human --- Reproductive Indices, Human --- Reproductive Periods --- HIV Coinfection --- HTLV-III Infections --- HTLV-III-LAV Infections --- T-Lymphotropic Virus Type III Infections, Human --- Coinfection, HIV --- Coinfections, HIV --- HIV Coinfections --- HIV Infection --- HTLV III Infections --- HTLV III LAV Infections --- HTLV-III Infection --- HTLV-III-LAV Infection --- Infection, HIV --- Infection, HTLV-III --- Infection, HTLV-III-LAV --- Infections, HIV --- Infections, HTLV-III --- Infections, HTLV-III-LAV --- T Lymphotropic Virus Type III Infections, Human

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Despite decades of developments in immunization and drug therapy, tuberculosis remains among the leading causes of human mortality, and no country has successfully eradicated the disease. Reenvisioning tuberculosis from the perspective of population biology, this book examines why the disease is so persistent and what must be done to fight it. Treating tuberculosis and its human hosts as dynamic, interacting populations, Christopher Dye seeks new answers to key questions by drawing on demography, ecology, epidemiology, evolution, and population genetics. Dye uses simple mathematical models to investigate how cases and deaths could be reduced, and how interventions could lead to TB elimination.Dye's analysis reveals a striking gap between the actual and potential impact of current interventions, especially drug treatment, and he suggests placing more emphasis on early case detection and the treatment of active or incipient tuberculosis. He argues that the response to disappointingly slow rates of disease decline is not to abandon long-established principles of chemotherapy, but to implement them with greater vigor. Summarizing epidemiological insights from population biology, Dye stresses the need to take a more inclusive view of the factors that affect disease, including characteristics of the pathogen, individuals and populations, health care systems, and physical and social environments.In broadening the horizons of TB research, The Population Biology of Tuberculosis demonstrates what must be done to prevent, control, and defeat this global threat in the twenty-first century.

Mycobacterium tuberculosis. --- Tuberculosis --- Consumption (Disease) --- Lungs --- Phthisis --- Pulmonary tuberculosis --- TB (Disease) --- Chest --- Mycobacterial diseases --- Mycobacterium tuberculosis --- Koch bacillus --- Tubercle bacillus --- Mycobacterium --- Tuberculin --- Epidemiology. --- Diseases --- Africa. --- China. --- DOTS strategy. --- HIV coinfection. --- HIV infection. --- HIV/AIDS. --- India. --- Kiribati. --- South Africa. --- TB control. --- TB elimination. --- TB infection. --- TB prevention. --- TB transmission. --- absolute reproductive fitness. --- antiretroviral therapy. --- chemotherapy. --- comparative risk assessment. --- demography. --- diagnosis. --- diseases. --- drug resistance. --- drug therapy. --- drug treatment. --- dynamic risk assessment. --- ecology. --- empirical epidemiology. --- environmental science. --- epidemiological models. --- epidemiology. --- etiology. --- evolution. --- exposure risk. --- genetic variation. --- geographical distribution. --- health services. --- immunization. --- incidence rates. --- infection. --- infectiousness. --- isoniazid preventive therapy. --- mortality. --- population biology. --- population genetics. --- reinfection. --- relapse. --- reproductive fitness. --- resistant strains. --- risk factors. --- risk. --- social disease. --- tuberculosis.

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Acquired Immunodeficiency Syndrome. --- HIV Infections. --- HTLV-III Infections --- HTLV-III-LAV Infections --- T-Lymphotropic Virus Type III Infections, Human --- HIV Infection --- HTLV III Infections --- HTLV III LAV Infections --- HTLV-III Infection --- HTLV-III-LAV Infection --- Infection, HIV --- Infection, HTLV-III --- Infection, HTLV-III-LAV --- Infections, HIV --- Infections, HTLV-III --- Infections, HTLV-III-LAV --- T Lymphotropic Virus Type III Infections, Human --- Acquired Immune Deficiency Syndrome --- Acquired Immuno-Deficiency Syndrome --- AIDS --- Immunodeficiency Syndrome, Acquired --- Immunologic Deficiency Syndrome, Acquired --- Acquired Immuno Deficiency Syndrome --- Acquired Immuno-Deficiency Syndromes --- Acquired Immunodeficiency Syndromes --- Immuno-Deficiency Syndrome, Acquired --- Immuno-Deficiency Syndromes, Acquired --- Immunodeficiency Syndromes, Acquired --- Syndrome, Acquired Immuno-Deficiency --- Syndrome, Acquired Immunodeficiency --- Syndromes, Acquired Immuno-Deficiency --- Syndromes, Acquired Immunodeficiency --- CD4-Positive T-Lymphocytes --- HIV-1 --- AIDS Arteritis, Central Nervous System --- AIDS (Disease) --- Acquired Immunodeficiency Syndrome --- HIV Infections --- HIV Coinfection --- Coinfection, HIV --- Coinfections, HIV --- HIV Coinfections --- Acquired immune deficiency syndrome --- Acquired immunodeficiency syndrome --- Acquired immunological deficiency syndrome --- HIV infections --- Immunological deficiency syndromes --- Virus-induced immunosuppression --- Treatment

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AIDS (Disease) --- Acquired Immunodeficiency Syndrome --- HIV Infections --- Acquired Immunodeficiency Syndrome. --- HIV Infections. --- HTLV-III Infections --- HTLV-III-LAV Infections --- T-Lymphotropic Virus Type III Infections, Human --- HIV Infection --- HTLV III Infections --- HTLV III LAV Infections --- HTLV-III Infection --- HTLV-III-LAV Infection --- Infection, HIV --- Infection, HTLV-III --- Infection, HTLV-III-LAV --- Infections, HIV --- Infections, HTLV-III --- Infections, HTLV-III-LAV --- T Lymphotropic Virus Type III Infections, Human --- Acquired Immune Deficiency Syndrome --- Acquired Immuno-Deficiency Syndrome --- AIDS --- Immunodeficiency Syndrome, Acquired --- Immunologic Deficiency Syndrome, Acquired --- Acquired Immuno Deficiency Syndrome --- Acquired Immuno-Deficiency Syndromes --- Acquired Immunodeficiency Syndromes --- Immuno-Deficiency Syndrome, Acquired --- Immuno-Deficiency Syndromes, Acquired --- Immunodeficiency Syndromes, Acquired --- Syndrome, Acquired Immuno-Deficiency --- Syndrome, Acquired Immunodeficiency --- Syndromes, Acquired Immuno-Deficiency --- Syndromes, Acquired Immunodeficiency --- Acquired immune deficiency syndrome --- Acquired immunodeficiency syndrome --- Acquired immunological deficiency syndrome --- HIV --- epidemiology --- HIV Coinfection --- Coinfection, HIV --- Coinfections, HIV --- HIV Coinfections --- CD4-Positive T-Lymphocytes --- HIV-1 --- AIDS Arteritis, Central Nervous System --- HIV infections --- Immunological deficiency syndromes --- Virus-induced immunosuppression --- aids --- hiv --- Urology. Andrology

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AIDS (Disease) --- HIV infections --- AIDS vaccines --- HIV Infections. --- HIV Infections --- AIDS vaccines. --- HIV infections. --- Treatment --- therapy. --- Treatment. --- HTLV-III Infections --- HTLV-III-LAV Infections --- T-Lymphotropic Virus Type III Infections, Human --- HIV Infection --- HTLV III Infections --- HTLV III LAV Infections --- HTLV-III Infection --- HTLV-III-LAV Infection --- Infection, HIV --- Infection, HTLV-III --- Infection, HTLV-III-LAV --- Infections, HIV --- Infections, HTLV-III --- Infections, HTLV-III-LAV --- T Lymphotropic Virus Type III Infections, Human --- HIV disease vaccines --- HIV (Viruses) infections --- HTLV-III infections --- HTLV-III-LAV infections --- Human T-lymphotropic virus III infections --- Acquired immune deficiency syndrome --- Acquired immunodeficiency syndrome --- Acquired immunological deficiency syndrome --- HIV Coinfection --- Coinfection, HIV --- Coinfections, HIV --- HIV Coinfections --- Viral vaccines --- Lentivirus infections --- Sexually transmitted diseases --- Immunological deficiency syndromes --- Virus-induced immunosuppression